Annotation Detail
Information
- Associated Genes
- HRAS
- Associated Variants
-
HRAS MUTATION
HRAS MUTATION - Associated Disease
- Merkel cell carcinoma
- Source Database
- DisGeNET
- Description
- In addition to previously identified mutations in TP53, RB1, and PIK3CA, we discovered activating mutations of oncogenes, including HRAS and loss-of-function mutations in PRUNE2 and NOTCH family genes in MCPyV-negative MCC.
- Pubmed
- 26238782
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs