chr11:32387775:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr11:32,409,321-32,457,110 
hg38 chr11:32,387,775-32,435,564

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.008 squamous cell carcinoma NA BeFree,LHGDN Detail
<0.001 Congenital chromosomal disease NA BeFree Detail
0.120 Colonic Neoplasms NA CTD_human Detail
<0.001 colorectal carcinoma NA BeFree Detail
<0.001 cryptorchidism NA BeFree Detail
<0.001 Diabetic Nephropathy NA BeFree Detail
<0.001 Down syndrome NA BeFree Detail
0.005 Endometrial Neoplasms NA LHGDN Detail
<0.001 endometriosis NA BeFree Detail
<0.001 Eosinophilia NA BeFree Detail
0.002 Disorder of eye NA GAD Detail
<0.001 Fanconi anemia NA BeFree Detail
0.003 Fibrosis NA LHGDN Detail
0.124 glioblastoma NA BeFree,CTD_human,LHGDN Detail
0.004 Glioma NA BeFree,LHGDN Detail
0.123 glomerulonephritis NA CTD_human,LHGDN Detail
0.008 Focal glomerulosclerosis NA BeFree,GAD,LHGDN Detail
0.002 gonadal dysgenesis NA BeFree Detail
<0.001 hemangioma NA BeFree Detail
<0.001 Hemangiosarcoma NA BeFree Detail
<0.001 Hematological Disease We determined the level of WT1 gene expression in 130 children, adolescents and ... BeFree 25238704 Detail
0.120 Diaphragmatic hernia NA BeFree,CTD_human Detail
<0.001 HIV Infections NA BeFree Detail
0.003 hyperparathyroidism NA BeFree,LHGDN Detail
<0.001 Hypertensive disease NA BeFree Detail
<0.001 male infertility Large multicenter studies are needed to fully assess the contribution of WT1 gen... BeFree 25451826 Detail
0.001 Kidney Diseases NA BeFree Detail
0.003 Kidney Failure, Chronic NA BeFree,GAD Detail
0.007 Kidney Neoplasm Studies of WT1-knockout mice confirmed the important role of WT1 in the pathogen... BeFree,GAD 25189877 Detail
<0.001 leiomyosarcoma NA BeFree Detail
0.143 leukemia Of these, 230 were monitored concurrently for minimal residual disease (MRD) by ... BeFree,CTD_human,LHGDN 24631740 Detail
<0.001 Leukemia, Eosinophilic, Acute NA BeFree Detail
<0.001 lymphoid leukemia NA BeFree Detail
0.002 Acute lymphocytic leukemia NA BeFree Detail
<0.001 Leukemia, Lymphocytic, Acute, L1 Studies of WT1-knockout mice confirmed the important role of WT1 in the pathogen... BeFree 25189877 Detail
0.008 myeloid leukemia NA BeFree,GAD Detail
0.128 Myeloid Leukemia, Chronic NA BeFree,CTD_human,GAD Detail
0.002 Leukemia, Myelomonocytic, Chronic NA GAD Detail
<0.001 Liver diseases NA BeFree Detail
<0.001 Liver neoplasms NA BeFree Detail
0.120 Lung Neoplasms NA CTD_human Detail
0.006 lymphoma NA BeFree,LHGDN Detail
<0.001 Malignant neoplasm of stomach Immunohistochemical study showed that Rad54 and XRCC2 proteins were highly expre... BeFree 25418835 Detail
0.003 medulloblastoma NA LHGDN Detail
0.003 melanoma A subtraction tolerization method of immunization allowed for Wilms' tumor prote... BeFree,LHGDN 25205401 Detail
<0.001 meningioma NA BeFree Detail
0.006 Mental Retardation NA BeFree Detail
<0.001 Myelodysplasia NA BeFree Detail
0.008 Neoplasm Metastasis NA LHGDN Detail
0.002 Pathologic Neovascularization NA GAD Detail
0.444 nephroblastoma Of these, 230 were monitored concurrently for minimal residual disease (MRD) by ... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 24631740 Detail
0.444 nephroblastoma Loss of BRCA1 expression and Wilms tumor 1 (WT-1) overexpression were detected b... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 24681740 Detail
0.444 nephroblastoma To investigate frequency and prognostic impact of Wilms tumor 1 (WT1) mutations ... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25110071 Detail
0.444 nephroblastoma Studies of WT1-knockout mice confirmed the important role of WT1 in the pathogen... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25189877 Detail
0.444 nephroblastoma Two CpGs located in the genes Wilms' tumor 1 (WT1) and potassium voltage-gated c... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25429063 Detail
0.444 nephroblastoma The expression of the Wilms tumor 1 (WT1), lutropin/choriogonadotropin receptor ... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25434310 Detail
0.444 nephroblastoma The Wilms' tumor 1 (WT1) expression has been recognized in a substantial number ... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25572170 Detail
0.444 nephroblastoma Individuals with WT1-positive acute myeloid leukemia (AML) in first (CR1) or sec... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25802083 Detail
0.444 nephroblastoma Wilms' tumor gene 1 (WT1) protein is a promising tumor-associated antigen for ca... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 25835542 Detail
0.444 nephroblastoma We also demonstrate that WT1(+) cells accumulate in fibrotic lung lesions, using... BeFree,CTD_human,GAD,LHGDN,ORPHANET,UNIPROT 26371248 Detail
0.026 nephrotic syndrome NA BeFree,GAD,LHGDN Detail
0.120 neurilemmoma NA CTD_human Detail
<0.001 obesity NA BeFree Detail
0.004 osteosarcoma NA BeFree,LHGDN Detail
<0.001 ovarian carcinoma NA BeFree Detail
0.122 Pancreatic Neoplasm NA CTD_human,GAD Detail
0.003 Preleukemia NA BeFree,GAD Detail
<0.001 pseudohermaphroditism NA BeFree Detail
<0.001 pulmonary fibrosis We also demonstrate that WT1(+) cells accumulate in fibrotic lung lesions, using... BeFree 26371248 Detail
<0.001 kidney failure NA BeFree Detail
<0.001 retinoblastoma NA BeFree Detail
<0.001 rhabdomyosarcoma Among neoplastic tissues, WT1 has been documented in the cytoplasm of benign and... BeFree 24709316 Detail
0.003 Sclerosis NA LHGDN Detail
0.003 Sertoli cell tumor NA LHGDN Detail
0.003 Thyroid Neoplasm NA LHGDN Detail
0.002 Tobacco use disorder NA GAD Detail
0.002 Turner syndrome NA BeFree Detail
0.001 Urogenital Abnormalities NA BeFree Detail
0.003 Fibromatosis, Aggressive NA BeFree,LHGDN Detail
0.002 Neoplasms, Second Primary NA GAD Detail
0.120 Ovarian Failure, Premature NA CTD_human Detail
0.005 acute leukemia NA BeFree Detail
<0.001 Adenocarcinoma of lung (disorder) NA BeFree Detail
<0.001 Malignant neoplasm of testis NA BeFree Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 Vascular anomaly NA BeFree Detail
<0.001 Congenital malformation of genital organs NA BeFree Detail
<0.001 Glomerulosclerosis (disorder) NA BeFree Detail
<0.001 Tumor Progression NA BeFree Detail
<0.001 follicular adenoma NA BeFree Detail
<0.001 Germ cell tumor NA BeFree Detail
0.246 WAGR syndrome NA BeFree,CTD_human,GAD,ORPHANET Detail
<0.001 Idiopathic hypereosinophilic syndrome NA BeFree Detail
<0.001 alveolar rhabdomyosarcoma NA BeFree Detail
0.005 smooth muscle tumor NA LHGDN Detail
0.001 gonadoblastoma NA BeFree Detail
<0.001 Neuroectodermal Tumor, Primitive NA BeFree Detail
<0.001 Sex cord-stromal tumor NA BeFree Detail
<0.001 Adult Acute Myeloblastic Leukemia NA BeFree Detail
0.002 pediatric acute myeloblastic leukemia NA BeFree Detail
<0.001 Congenital defects NA BeFree Detail
0.120 congenital diaphragmatic hernia NA BeFree,CTD_human Detail
<0.001 pancreatic carcinoma NA BeFree Detail
0.003 Gastrointestinal Stromal Tumors NA LHGDN Detail
<0.001 Defect of diaphragm NA BeFree Detail
0.001 Malignant neoplasm of lung Subsequent research has shown that the WT1 gene in many other cases acts as an o... BeFree 25189877 Detail
<0.001 Myofibroblastoma Wilms' tumor protein (WT1) in mammary myofibroblastoma: an immunohistochemical s... BeFree 24709316 Detail
0.005 Neoplasm, Residual Of these, 230 were monitored concurrently for minimal residual disease (MRD) by ... BeFree 24631740 Detail
<0.001 disseminated eosinophilic collagen disease NA BeFree Detail
<0.001 Dermatomyositis, Childhood Type NA BeFree Detail
<0.001 Renal glomerular disease NA BeFree Detail
<0.001 Metastatic melanoma The peptide WT1-pTj was also protective in vivo in a metastatic melanoma model a... BeFree 25205401 Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
<0.001 Conventional (Clear Cell) Renal Cell Carcinoma Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation st... BeFree 25025131 Detail
<0.001 extraosseous Ewings sarcoma-primitive neuroepithelial tumor NA BeFree Detail
0.003 Solid tumour NA BeFree Detail
<0.001 laryngeal squamous cell carcinoma NA BeFree Detail
0.130 desmoplastic small round cell tumor NA BeFree,ORPHANET Detail
<0.001 Segmental glomerulosclerosis NA BeFree Detail
<0.001 inflammatory myofibroblastic tumor Accordingly, we studied immunohistochemically the potential expression of WT1 in... BeFree 24709316 Detail
<0.001 malignant fibrous histiocytoma NA BeFree Detail
<0.001 sarcomatoid mesothelioma NA BeFree Detail
0.003 Endometrial Stromal Tumors NA LHGDN Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 malignant mesothelioma NA BeFree Detail
<0.001 Malignant Mesothelioma of Peritoneum NA BeFree Detail
<0.001 chronic eosinophilic leukemia NA BeFree Detail
<0.001 Malignant neoplasm of pancreas NA BeFree Detail
<0.001 Secondary malignant neoplasm of pancreas NA BeFree Detail
<0.001 Malignant neoplasm of prostate NA BeFree Detail
<0.001 Hematopoietic Neoplasms NA BeFree Detail
<0.001 Hematologic Neoplasms NA BeFree Detail
0.002 Steroid-resistant nephrotic syndrome NA BeFree Detail
<0.001 Bilateral Cryptorchidism As far as is known, this is the smallest deletion as-yet described encompassing ... BeFree 24912414 Detail
<0.001 Chromosome 8, trisomy NA BeFree Detail
<0.001 Sleep Apnea, Obstructive NA BeFree Detail
<0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Malignant glioma NA BeFree Detail
<0.001 Osteosarcoma of bone NA BeFree Detail
0.007 Carcinogenesis Wilms tumor 1 (WT1) protein, a transcription factor, is overexpressed in many tu... BeFree 25219513 Detail
0.002 Leukemogenesis NA BeFree Detail
<0.001 prostate carcinoma NA BeFree Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
0.003 breast carcinoma NA BeFree Detail
<0.001 Carcinoma of lung Subsequent research has shown that the WT1 gene in many other cases acts as an o... BeFree 25189877 Detail
<0.001 Ewings sarcoma-primitive neuroectodermal tumor (PNET) NA BeFree Detail
<0.001 colon carcinoma NA BeFree Detail
<0.001 stomach carcinoma Immunohistochemical study showed that Rad54 and XRCC2 proteins were highly expre... BeFree 25418835 Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 Idiopathic Inflammatory Myopathies NA BeFree Detail
<0.001 adult acute lymphocytic leukemia NA BeFree Detail
0.003 hypospadias NA BeFree,GAD Detail
<0.001 Testicular malignant germ cell tumor NA BeFree Detail
<0.001 Post MI NA BeFree Detail
<0.001 Epithelioid mesothelioma, malignant NA BeFree Detail
0.003 ovarian neoplasm NA BeFree,LHGDN Detail
0.573 Denys-Drash syndrome Heterozygous missense mutations in the WT1 gene that affect the function of the ... BeFree,CLINVAR,CTD_human,GAD,LHGDN,MGD,ORPHANET,UNIPROT 25613702 Detail
<0.001 Malignant neoplasm of ovary NA BeFree Detail
<0.001 Squamous cell carcinoma of the head and neck NA BeFree Detail
0.010 sarcoma NA BeFree,LHGDN Detail
<0.001 extraskeletal myxoid chondrosarcoma NA BeFree Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
0.003 Hepatic Insufficiency NA LHGDN Detail
<0.001 Eosinophilic disorder NA BeFree Detail
<0.001 Adenocarcinoma of large intestine NA BeFree Detail
<0.001 Nephrogenic rest NA BeFree Detail
<0.001 Childhood Renal Neoplasm NA BeFree Detail
<0.001 Malignant Vascular Neoplasm Among neoplastic tissues, WT1 has been documented in the cytoplasm of benign and... BeFree 24709316 Detail
<0.001 mesenchymal cell neoplasm The present study shows that mammary epithelioid cell MFB should be added to the... BeFree 24709316 Detail
<0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
<0.001 skull base meningioma NA BeFree Detail
<0.001 Spindle Cell Neoplasm NA BeFree Detail
<0.001 renal carcinoma NA BeFree Detail
0.142 Mammary Neoplasms NA BeFree,CTD_human,LHGDN Detail
<0.001 Autism Spectrum Disorders NA BeFree Detail
0.003 Desmoplastic NA BeFree Detail
<0.001 colorectal cancer NA BeFree Detail
0.003 hypereosinophilic syndrome NA BeFree,LHGDN Detail
<0.001 Non-Malignant Ascites Adverse Event NA BeFree Detail
<0.001 Glioblastoma multiforme This review describes the role of the Wilms tumor 1 gene (WT1) and its relations... BeFree 25434383 Detail
<0.001 Disorder characterized by eosinophilia NA BeFree Detail
<0.001 Penile hypospadias NA BeFree Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
<0.001 MYELOPROLIFERATIVE SYNDROME, TRANSIENT NA BeFree Detail
0.001 MULTICYSTIC RENAL DYSPLASIA, BILATERAL NA BeFree Detail
<0.001 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma NA BeFree Detail
0.004 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree,LHGDN Detail
0.004 liver carcinoma NA BeFree,LHGDN Detail
<0.001 Chronic kidney disease stage 5 NA BeFree Detail
<0.001 46, XY Disorders of Sex Development NA BeFree Detail
<0.001 Mixed phenotype acute leukemia NA BeFree Detail
0.001 Bilateral Wilms Tumor NA BeFree Detail
0.120 Meacham Winn Culler syndrome NA CTD_human Detail
<0.001 Juvenile dermatomyositis NA BeFree Detail
0.120 Deletion 11p13 NA ORPHANET Detail
<0.001 myeloid neoplasm Peptide vaccines are capable of eliciting immune responses targeting tumor-assoc... BeFree 25802083 Detail
0.240 Nephrotic syndrome, type 4 NA CTD_human,UNIPROT Detail
0.002 myelodysplastic syndrome NA GAD Detail
<0.001 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms Importantly, we stratify TNBCs into three distinct methylation clusters associat... BeFree 25641231 Detail
0.002 Cytogenetically normal acute myeloid leukemia NA BeFree Detail
0.002 Congenital Abnormality NA BeFree Detail
0.003 adenocarcinoma NA BeFree,LHGDN Detail
<0.001 adenoma NA BeFree Detail
0.005 Alzheimer's disease NA GAD,LHGDN Detail
<0.001 Anaplasia NA BeFree Detail
0.002 aniridia NA BeFree Detail
<0.001 autistic disorder NA BeFree Detail
<0.001 Beckwith-Wiedemann syndrome NA BeFree Detail
0.001 Blast Phase NA BeFree Detail
0.003 Malignant neoplasm of breast NA BeFree Detail
0.003 Carcinoid Tumor NA LHGDN Detail
<0.001 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
<0.001 Non-small cell lung carcinoma Immunohistochemical study showed that Rad54 and XRCC2 proteins were highly expre... BeFree 25418835 Detail
<0.001 renal cell carcinoma NA BeFree Detail
Annotation

Annotations

DescrptionSourceLinks
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We determined the level of WT1 gene expression in 130 children, adolescents and young adults with ma... DisGeNET Detail
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Large multicenter studies are needed to fully assess the contribution of WT1 genetic alterations to ... DisGeNET Detail
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Studies of WT1-knockout mice confirmed the important role of WT1 in the pathogenesis of Wilms' tumou... DisGeNET Detail
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Of these, 230 were monitored concurrently for minimal residual disease (MRD) by flow cytometry (FCM)... DisGeNET Detail
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Studies of WT1-knockout mice confirmed the important role of WT1 in the pathogenesis of Wilms' tumou... DisGeNET Detail
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Immunohistochemical study showed that Rad54 and XRCC2 proteins were highly expressed in the majority... DisGeNET Detail
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A subtraction tolerization method of immunization allowed for Wilms' tumor protein-1 (WT1) identific... DisGeNET Detail
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Of these, 230 were monitored concurrently for minimal residual disease (MRD) by flow cytometry (FCM)... DisGeNET Detail
Loss of BRCA1 expression and Wilms tumor 1 (WT-1) overexpression were detected by immunohistochemica... DisGeNET Detail
To investigate frequency and prognostic impact of Wilms tumor 1 (WT1) mutations (mut), we analyzed 3... DisGeNET Detail
Studies of WT1-knockout mice confirmed the important role of WT1 in the pathogenesis of Wilms' tumou... DisGeNET Detail
Two CpGs located in the genes Wilms' tumor 1 (WT1) and potassium voltage-gated channel, KQT-like sub... DisGeNET Detail
The expression of the Wilms tumor 1 (WT1), lutropin/choriogonadotropin receptor (LHR), 17-β-hydroxys... DisGeNET Detail
The Wilms' tumor 1 (WT1) expression has been recognized in a substantial number of acute myeloid leu... DisGeNET Detail
Individuals with WT1-positive acute myeloid leukemia (AML) in first (CR1) or second (CR2) remission ... DisGeNET Detail
Wilms' tumor gene 1 (WT1) protein is a promising tumor-associated antigen for cancer immunotherapy. DisGeNET Detail
We also demonstrate that WT1(+) cells accumulate in fibrotic lung lesions, using two different mouse... DisGeNET Detail
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We also demonstrate that WT1(+) cells accumulate in fibrotic lung lesions, using two different mouse... DisGeNET Detail
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Among neoplastic tissues, WT1 has been documented in the cytoplasm of benign and malignant vascular ... DisGeNET Detail
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Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, most promin... DisGeNET Detail
Wilms' tumor protein (WT1) in mammary myofibroblastoma: an immunohistochemical study. DisGeNET Detail
Of these, 230 were monitored concurrently for minimal residual disease (MRD) by flow cytometry (FCM)... DisGeNET Detail
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The peptide WT1-pTj was also protective in vivo in a metastatic melanoma model and peptide-stimulate... DisGeNET Detail
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Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell re... DisGeNET Detail
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Accordingly, we studied immunohistochemically the potential expression of WT1 in mammary myofibrobla... DisGeNET Detail
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As far as is known, this is the smallest deletion as-yet described encompassing the WT1 gene and was... DisGeNET Detail
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Wilms tumor 1 (WT1) protein, a transcription factor, is overexpressed in many tumors and plays a rol... DisGeNET Detail
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Subsequent research has shown that the WT1 gene in many other cases acts as an oncogene, most promin... DisGeNET Detail
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Immunohistochemical study showed that Rad54 and XRCC2 proteins were highly expressed in the majority... DisGeNET Detail
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Heterozygous missense mutations in the WT1 gene that affect the function of the wild-type allele hav... DisGeNET Detail
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Among neoplastic tissues, WT1 has been documented in the cytoplasm of benign and malignant vascular ... DisGeNET Detail
The present study shows that mammary epithelioid cell MFB should be added to the list of mesenchymal... DisGeNET Detail
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This review describes the role of the Wilms tumor 1 gene (WT1) and its relationship to GBM. DisGeNET Detail
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Peptide vaccines are capable of eliciting immune responses targeting tumor-associated antigens such ... DisGeNET Detail
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Importantly, we stratify TNBCs into three distinct methylation clusters associated with better or wo... DisGeNET Detail
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Immunohistochemical study showed that Rad54 and XRCC2 proteins were highly expressed in the majority... DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg38
Position
chr11:32,387,775-32,435,564
Variant Type
snv
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